1 edition of **Periodic optimization of biological systems** found in the catalog.

- 176 Want to read
- 10 Currently reading

Published
**1988** .

Written in English

- Chemotherapy,
- Mathematical optimization,
- Biological systems,
- Periodic functions,
- Cancer

**Edition Notes**

Statement | by Eva-Maria Abulesz |

The Physical Object | |
---|---|

Pagination | viii, 136 leaves : |

Number of Pages | 136 |

ID Numbers | |

Open Library | OL25904116M |

OCLC/WorldCa | 19935932 |

Conference: Proposed for presentation at the Fourth International Conference on Automatic Differentiation held July , in Chicago, IL. In this paper the general opinion about automatic control of ion accelerators is described, explaining the differences between steady-state and dynamic models of a control system. Three steps describing a steady-state model are given. Subsequently, a new method for solving a set of nonlinear Missing: biological systems. Mainul Haque. I'm a Lecturer in Applied Mathematics at the University of this, I was a MOD (Ministry of Defense) Research Fellow and EPSRC (Engineering and Physical Research Council) Research Associate at the Division of Clinical Neuroscience under the directorship of Jonathan G Hardman at the School of Medicine, University of. Professor Emeritus. Technical University of Denmark. okt. – nu9 år 8 måneder. Department of Physics. Further studies of nonlinear dynamic phenomena in physical, technical and biomedical systems. V. Avrutin, E. Mosekilde, Zh. Zhusubaliyev, and L. Gardini: Onset of Chaos in Single Phase Power Electronic Inverter, Chaos 25 () Title: Professor Emeritus at Technical .

In recent years experimental and numerical studies have shown that chaos is a widespread phenomenon throughout the biological hierarchy ranging from simple enzyme reactions to ecosystems. Although a coherent picture of the fundamental mechanisms responsible for chaotic dynamics has started to.

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Statistical Optimization of Biological Systems 1st Edition by Tapobrata Panda (Author), Thomas Theodore (Author), R. Arun Kumar (Author) 0 more ISBN Cited by: 5. Background. Systems biology allows the analysis of biological systems behavior under different conditions through in silicoexperimentation.

The possibility of perturbing biological systems in different manners calls for the design of perturbations to achieve particular goals. Examples would include, the design of a chemical stimulation to maximize the amplitude of a given cellular signal or to achieve a desired pattern in pattern formation systems Cited by: Barbu V.

() Optimal control of periodic systems. In: Malanowski K. Nahorski Z.Peszyńska M. (eds) Modelling and Optimization of Distributed Parameter Systems Applications to engineering. IFIP - The International Federation for Information by: 2. The reason why the single optimization framework can be used to express the three dynamics is not a mere coincidence nor just a mathematical property, but the biological nature of the dynamics that the biological systems have time development in the interactions among their components, and the variation of each component has the by: 1.

This book is split into four parts. The rst part covers the All elements within the same group in the periodic table are isosteres of each other. Therefore, silicon and carbon are isosteres of each other, as are oxygen Quite often during and after optimization of the direct biological response, it will be important to also optimize.

In book: System Modelling and Optimization (pp) ecological and biological systems, economic systems, etc. Periodic environmental shifts have been used to induce synchrony in many. Journal of Biological Systems() Periodic solution for the stochastic chemostat with general response function.

Physica A: Statistical Mechanics and its ApplicationsAbstract. Optimization, quantitative, aims for the most favorable options in process behavior as guided by optimal, that is, maximal and minimal values of a chosen performance measure. A wide spectrum of optimization infrastructure is represented here by four approaches.

(1) Classical optimization employs the first derivative of a well-defined mathematical function as used in calculus. As an example for a biological motion powered by muscles, we present periodic single-arm self-stabilizing juggling motions involving three muscles that have been produced by numerical optimization.

The stability of a periodic motion can be measured in terms of the spectral radius of. The papers cover a broad range of topics within control theory.

Optimization problems arising in the design of efficient controllers for neuronal, cardiac, and motor systems are discussed in [2, 7, 28, 29].

Optimal feedback controls Footnote 2 intrinsic to the organism are analyzed for homeostasis of blood pressure [] and neuronal firing rates []. One paper [] discusses optimizing a new approach. 1. Introduction. Periodic rhythms are regular behaviours in biological systems [].

For instance, the circadian clock helps regulate sleep schedule, body temperature, hormone levels in a daily cycle []; monthly rhythms are reflected in reproductive cycles of many marine plants and animals []; annual rhythms are expressed in flowering, migration, hibernation or the reproduction and growth of Cited by: 1.

A competition model involving two competing predator species and a single renewable resource prey species is studied under the assumption that the system parameters are periodic in time. It is shown by means of global bifurcation techniques that a continuum of positive periodic solutions exists as a function of a selected (averaged) parameter and that the stability of these solutions (at least locally near bifurcation) depends on the direction of bifurcation.

The focus of the work is twofold. First, it provides an introduction into fundamental structural and behavioral aspects of periodic review inventory systems.

Second, it includes a comprehensive study on analytical and optimization aspects of a specific class of those systems.

For the latter. This book provides an overview of computational methods as well as as their application to problems of molecular biophysics. Seven chapters deal with the methodology, enzymes and other proteins, nucleic acids, carbohydrates, hydration and hydrophobic effects concerning biomolecular g: Periodic optimization.

Journal of Biological Systems() Periodic solutions for a seasonally forced SIR model with impact of media coverage. Advances in Difference Equations Khandelwal A, Lukacova V, Comez D, Kroll DM, Raha S, Balaz S () A combination of docking, QMMM methods, and MD simulation for binding affinity estimation of metalloprotein ligands.

J Med Chem 48 (17) CrossRef Google Scholar. Software Tools and Algorithms for Biological Systems, () Reducible Volterra and LevinNohel Retarded Equations with Infinite Delay. Journal of. This paper describes techniques for computing periodic orbits in systems of hybrid differential-algebraic equations and parameter estimation methods for fitting these orbits to data.

These techniques make extensive use of automatic differentiation to evaluate derivatives accurately and effciently for time integration, parameter sensitivities, root finding and optimization. This book offers an introduction to the theory of non-autonomous and stochastic dynamical systems, with a focus on the importance of the theory in the Applied Sciences.

More specifically, the technique which is adopted is provided by the recently developed theory of periodic optimal control [5]. This theory perfectly matches the problem to be dealt with and, as recognized in [6], can be expected to play an important role in the management of biological systems.

Some well-known autocatalytic reaction systems are periodic in time and sometimes are called biological clocks. Turings instabilities, published insuggested that the morphogens transported by diffusion and other mechanisms from a production site may cause the patterning of biological host tissues during the growth phase.

J. Bmmcchapio. Vol. 9, pp. ( Pergamon Press Printed in Great Britain A METHOD FOR DESCRIBING THE MOTION OF BIOLOGICAL SYSTEMS H. HATZE National Research Institute for Mathematical Sciences, CSIR, P.

BoxPretoriaSouth Africa Abstract-The concept of biomotion as a quantifiable kinematic entity, characterized by its inherent non-repeatability. In this course the participants learn how to describe the dynamic behavior of biological systems, and how to use optimization techniques to solve a variety of problems in bioinformatics and systems biology.

Concepts of modelling in terms of differential equations are introduced via a great variety of case studies taken from diverse practices.

The book What Is Life. grew out of a paper, Toward a General Theory of Evolution: Extending Darwinian Theory to Inanimate Matter, Pross published in the Journal of Systems.

Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group.

It does touch on solutions of linear systems, periodic solutions, as well as linear stability analysis of nonlinear systems. The second semester continues with stability analysis, Floquet theory, the Poincare-Bendixson theorem as well as some topics from dynamical systems theory.

Abstract. This chapter focuses on dynamical behavior of lattice models arising in the biological sciences, in particular, attractors for such systems. Three types of lattice dynamical systems are. Journal of Biological SystemsSIAM Journal on Control and Optimization() The Existence of Periodic Solutions to Reaction-Diffusion Systems with Periodic Data.

SIAM Journal on Mathematical AnalysisAbstract | PDF. See How Photonic Systems in Nature Work The book presents important examples of how combining biological inspiration with state-of-the-art nanoscience is resulting in the emergence of a field. Publisher preview available. Optimal phase control of biological oscillators using augmented phase reduction.

April ; Biological Cybernetics (). 1st BCAM Workshop on Nonlinear dynamics in Biological Systems BOOK OF ABSTRACTS Oral contributions: Jacobo Aguirre Centro de Astrobiología (CSIC-INTA) the stability of observed periodic solutions. Dynamics of the saline oscillator Diandian Chen and optimization of these selective drugs against certain cell-based diseases, such as.

This book is an introduction to the principles and practice of mathematical modeling in the biological sciences, concentrating on applications in population biology, epidemiology, and resource management. The core of the book covers models in these areas and the mathematics useful in analyzing them, including case studies representing real-life situations.

55(2). Period of real structures in different biological systems has a wide range of dimensions (from 1 to μm), but typically 110 μm. So our unit of length corresponds to 110 μm. Below, for the sake of clarity, we will take that and characterize the system by the remaining free parameters: relative elasticity and external velocity.

The goal of the University of Florida's Retrospective Dissertation Scanning project is to build a digital collection of approximately 8, dissertations written by PhD graduates of the University of Florida from This page is the portal to the UF dissertations scanned and made available via the Internet Archive up to this point.

This chapter takes a robust control approach to the robustness of oscillatory behavior, using oscillations in the social amoeba Dictyostelium as an illustrative example. It uses the proposed methods to examine the robustness of oscillations in the concentration of adenosine 3, 5-cyclic monophosphate (cAMP) observed during the aggregation phase of starvation-induced development in.

Optimization of biological processes can produce economic advantage when applied to biotechnilogical processes such as waste treatment or remediation. This study examines biological process optimization through the use of several mathematical techniques including random search, hill-climbing, local search and genetic algorithms.

The Periodic Table of Life (PeTaL) is a system design tool and open source framework that uses artificial intelligence (AI) to aid in the systematic inquiry of nature for its application to human systems.

This paper defines PeTaLs architecture and workflow. Biomimicry, biophysics, biomimetics, bionics and numerous other terms refer to the use of biology and biological principles to inform. Introduction. External and internal periodic oscillations play an important role in intracellular and extracellular biomedical systems and have attracted enormous research interest (see e.

and the references therein). Proper functioning of cells that are exposed to such periodic signals requires internal biological mechanisms that are able to synchronize with the periodic excitation.

The U. Department of Energy's Office of Scientific and Technical Information. We present a specific mathematical programming problem that allows us to obtain the optimal parameters for mechanical systems' stabilizers.

The general approach is described, and the method is applied to optimization of two mechanical systems, namely, a harmonic oscillator and a satellite with gravitational stabilizer. CP2K – atomistic simulations of solid state, liquid, molecular and biological systems.

CP2K is a free and open source quantum chemistry and solid state physics software package that can perform atomistic simulations of solid state, liquid, molecular, periodic, material, crystal, and biological systems.

It’s especially aimed at massively parallel and linear scaling electronic structure methods and state-of-the .Analogously, the periodic table of cell types could be used to predict a species’ missing cell types, based on the biological logic of development and differentiation.

For example, for a given species, the periodic table of cell types may help in revealing missing cell populations in a specific developmental by: Research interests: Starting in and after 12 years of working on the stability of power electronics systems, I have gradually expanded my research area into non-linear and non-stationary signal analysis, from the domain of harmonics in power systems into the domain of biological systems.